Quote:
Originally Posted by Lauren Summerhill
Which makes me wonder if one can sleep through that much pain without waking up?
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Lauren, if you had to pick three things that modern medicine should know about it and doesn't, I would put pain, obesity, and sleep at the top of the list.
One biologist made the point that sleep had to be so advantageous to a species because it left them so vulnerable while asleep. IOW, the advantages of sleep trump the vulnerability of sleeping in the wild.
Sleep and pain are related though. Anyone who is deprived of sleep for 48 hours will develop the terrible tender points commonly seen with fibromyalgia.
There seems to be production of important hormones that are made during sleep that can't be made at any other time. I know some of the hormones that are made in the pituitary correlate with certain phases of sleep.
But what you are talking about is natural pain killers, the endorphins. Could they be so high in sleep that you literally sleep right through an event that is quite painful? I don't know for sure, but my guess is that they probably could be. Right now, we only know about three classes of endorphins, but I suspect there are more.
Your body actually makes its own form of marijuana called Anandamide, and there is cross reactivity between it and endorphins.
The weirdest of the three classes of endorphins IMO is dynorphin. It is like 100X stronger than morphine but unlike endorphin which is effective against neuropathic pain, it makes neuropathic pain worse.
When you inject dynorphin into a rat's spinal cord, they suffer from allodynia, pain from nonpainful stimuli like moderately hot water or a bright light. However, they don't suffer or suffer much less from somatic pain (like an ovarian cyst bursting or a leg being broken).
But I don't know the correlation between sleep and endophins though. Maybe someone else does.