Antibiotic-resistant diseases ot produce epidemics?

[Guest032516]

Any ideas on whether this is an exaggerated concern (at least right now) or is the sky really falling? Here is the link:

http://www.guardian.co.uk/society/20...alyptic-threat

This quote is hard to believe:
-------------------------
"Drug resistance is emerging in diseases across the board. Davies said 80% of gonorrhea was now resistant to the frontline antibiotic tetracycline, and infections were rising in young and middle-aged people. Multi-drug resistant TB was also a major threat, she said."
-------------------------
80% of all gonorrhea cases are resistant to ALL drugs or just tetracycline?

This doesn't look good.

[CuteOldGuy]

Why should we worry. Once the government is in control of the health system, everything will be fine.

[joe bloe]

Originally Posted by ExNYer

Any ideas on whether this is an exaggerated concern (at least right now) or is the sky really falling? Here is the link:

http://www.guardian.co.uk/society/20...alyptic-threat

This quote is hard to believe:
-------------------------
"Drug resistance is emerging in diseases across the board. Davies said 80% of gonorrhea was now resistant to the frontline antibiotic tetracycline, and infections were rising in young and middle-aged people. Multi-drug resistant TB was also a major threat, she said."
-------------------------
80% of all gonorrhea cases are resistant to ALL drugs or just tetracycline?

This doesn't look good.

That reminds me of something Jeremiah Wright said. Wright contended that the United States government invented HIV in order to kill African Americans. Wright is a raving lunatic and Barack Obama went to his chuch for twenty years.

http://www.dailymotion.com/video/xgj...eated-hiv_news

[Old-T]

Originally Posted by CuteOldGuy

Why should we worry. Once the government is in control of the health system, everything will be fine.

Originally Posted by joe bloe

That reminds me of something Jeremiah Wright said. Wright contended that the United States government invented HIV in order to kill African Americans. Wright is a raving lunatic and Barack Obama went to his chuch for twenty years.

http://www.dailymotion.com/video/xgj...eated-hiv_news

Nice of both of you to chime in with stupid comments.

Unfortunately I may be disapointed, but certainly not surprised.

[CuteOldGuy]

You know, Old-T, so many on here chime in with stupid comments on threads started by Joe, me, and others, and no one calls them on it. But Joe and I comment, and you jump in. Yes, this is a serious problem, but you know that many on here are going to call for more government to fight it. I was just beating them to it. And Joe made a good point about people Obama associates with who think the government created AIDS to decimate those of African descent.

So shove your sanctimony up your ass.

[Guest032516]

Originally Posted by joe bloe

That reminds me of something Jeremiah Wright said. Wright contended that the United States government invented HIV in order to kill African Americans. Wright is a raving lunatic and Barack Obama went to his chuch for twenty years.

http://www.dailymotion.com/video/xgj...eated-hiv_news

Give it a fucking rest, will you? Try to stay on topic.

I'm sure a fingernail clipper also reminds you of SOMETHING bad about Barack Obama. We just don't need to hear it in every thread.

[Guest032516]

Originally Posted by CuteOldGuy

You know, Old-T, so many on here chime in with stupid comments on threads started by Joe, me, and others, and no one calls them on it. But Joe and I comment, and you jump in.

I'm sure they do chime in on threads you start.

But that may be because the topic of the thread you started is often ridiculous or at least controversial to start with. So it invites a similar response.

But this thread isn't some conspiracy mongering thread. It isn't bashing Obama. It isn't bashing Bush. It isn't blaming unions or bankers or the French for all the world troubles.

Originally Posted by CuteOldGuy

And Joe made a good point about people Obama associates with who think the government created AIDS to decimate those of African descent.

To the extent Joe had a point, his hair is covering it nicely.

[i'va biggen]

Originally Posted by ExNYer

Any ideas on whether this is an exaggerated concern (at least right now) or is the sky really falling? Here is the link:

http://www.guardian.co.uk/society/20...alyptic-threat

This quote is hard to believe:
-------------------------
"Drug resistance is emerging in diseases across the board. Davies said 80% of gonorrhea was now resistant to the frontline antibiotic tetracycline, and infections were rising in young and middle-aged people. Multi-drug resistant TB was also a major threat, she said."
-------------------------
80% of all gonorrhea cases are resistant to ALL drugs or just tetracycline?

This doesn't look good.

Use a cover this is real has been talked about quite a bit.Results from people not finishing the drug regimen leaves some alive and able to resist the drug.

[Guest032516]

Originally Posted by i'va biggen

Use a cover this is real has been talked about quite a bit.Results from people not finishing the drug regimen leaves some alive and able to resist the drug.

Use a cover, not doubt.

But I think you can spread gonorrhea even from oral, can't you?

That means NO getting BBBJs any more either. But I guess you can't even French kiss then, can you?

[joe bloe]

Originally Posted by Old-T

Nice of both of you to chime in with stupid comments.

Unfortunately I may be disapointed, but certainly not surprised.

If any Republican president or presidential candidate had a close friendship with a hate monger like Jeremiah Wright, you'd be the first to say it made him unfit to hold office.

Liberals give Obama a pass on his twenty year relationship with Wright, a hate monger racist anti-semite. Trent Lott made one sympathetic comment about Strom Thurmond at his one hundredth birthday party and liberals went berserk.

[TheDaliLama]

BareBackBigLouie is not going to like this.

[WTF]

Originally Posted by ExNYer

But this thread isn't some conspiracy mongering thread. It isn't bashing Obama. It isn't bashing Bush. It isn't blaming unions or bankers or the French for all the world troubles.


.

Good luck ExNYer...jb and COG always plays Six Degree's of seperation and all evil leads back to Obama!

[Sidewinder]

Originally Posted by ExNYer

Any ideas on whether this is an exaggerated concern (at least right now) or is the sky really falling? Here is the link:

http://www.guardian.co.uk/society/20...alyptic-threat

This quote is hard to believe:
-------------------------
"Drug resistance is emerging in diseases across the board. Davies said 80% of gonorrhea was now resistant to the frontline antibiotic tetracycline, and infections were rising in young and middle-aged people. Multi-drug resistant TB was also a major threat, she said."
-------------------------
80% of all gonorrhea cases are resistant to ALL drugs or just tetracycline?

This doesn't look good.

I've been following STD treatment guidelines for several years now. I do not recall tetracycline *EVER* being in the list of recommended antibiotics for gonorrhea.

I did encounter a physician some years ago who believed that the usual doxycycline regimen (100 mg by mouth twice daily for 10 days) was effective against gonorrhea. I do not know if he was correct or not. The CDC strongly prefers single-dose regimens for sexually-transmitted diseases, as the dose can be given and witnessed in the doctor's office, guaranteeing proper compliance.

Ciprofloxacin was the recommended antibiotic for gonorrhea for some years, until resistant strains showed up. Ceftriaxone, cefixime, and spectinomycin were all alternatives.

Spectinomycin production halted world-wide some years ago. Not enough profit, or something.

Japan managed to breed a cefixime-resistant strain, and it has started to show up in North America. Ceftriaxone, given by intramuscular injection, is still effective. At the same time, the CDC doubled the recommended ceftriaxone dosage a year or two ago, and more recently added a recommendation for co-treatment with azithromycin 1000 mg by mouth single dose. (US physicians routinely did the co-treatment anyway, as azithromycin 1000 mg is the standard single-dose treatment for chlamydia, and chlamydia and gonorrhea routinely cohabitate. Chlamydia is frequently asymptomatic.)

Multiple-drug-resistant (MDR) and extremely-drug-resistant tuberculosis is a real and growing problem. Antibiotic-resistant staph (MRSA and related nasties) is also a real issue.

That's only part of the story. What is not really appreciated in some circles is the importance of antibiotics in surgery, and especially recovery from major orthopedic surgery. Fifty years ago, before penicillin, a post-operative infection on an orthopedic surgery wound site, that by definition opened a pathway all the way to the bone, was a very ugly death sentence. There wasn't anything the doctors could do. About their only hope was observing proper sterile and antiseptic procedure, and hoping no infection started. Today, post-op infections are considered routine nuisances, occurring in about 3% of cases even with the best of sterile procedure, and easily treated with modern antibiotics.

Meanwhile, we have no new antibiotics coming down the pike in the development process. The FDA's rules have always made drug development a very difficult, very lengthy, very expensive process, and the recent rule changes that all but shut down the pharmaceuticals industry is not helping any.

For gonorrhea, there are still one or two options. Spectinomycin production could be restarted. Cefixime was unavailable in the US for several years, and is becoming available again. Also, according to the prescribing literature, there is some evidence that azithromycin 2000 mg by mouth single dose is effective against gonorrhea. (However, 2 grams of azithromycin is going to be VERY rough on the patient's stomach, probably a lot less fun than clindamycin - which is NO picnic on an empty stomach, let me tell you.)

Summary: Yes, we have a problem developing.

[Guest032516]

Thank you for an excellent informative answer.

[Old-T]

Originally Posted by joe bloe

If any Republican president or presidential candidate had a close friendship with a hate monger like Jeremiah Wright, you'd be the first to say it made him unfit to hold office.

Liberals give Obama a pass on his twenty year relationship with Wright, a hate monger racist anti-semite. Trent Lott made one sympathetic comment about Strom Thurmond at his one hundredth birthday party and liberals went berserk.

You aren't even close to the truth on your comments, but that isn't the point. The point is exactly what EXNYer said: some folks (you and COG are prototypes, as are some on the liberal fringe) just can't talk about anything without turning it into a Bash The Pres (or Ex-Pres depending upon what flavor wacko they are).

This thread was not about Wright, or gays, of Rove, or Obama--but that didn't stop your irrational one size fits all hatred from showing through. And contrary to GOG's rant, the AIDs comment is indeed stupid--just like the RWW flat earth and creationists--but that too has little to do with the topic, so whay bring it up?

Wright is a hate monger, as was Thurmond. Both are wrong. People who stick up for hate mongers are wrong, but I never felt one stupid comment by Lott was reason for him to go (though I suspect it may have been how he really felt, I don't know for sure). I didn't think Rush should have been fired from his football gig either (though I though he was far from a good sports commentator). But for you to toss them into a conversation that has nothing to do with them is truly symptomatic of an obsessed mind.